SCHEMBL14766705

SCHEMBL14766705

CCCCOc1ccc(/C=C/c2ccc(-c3ccc(C4CCC(OCCC)CC4)c(F)c3F)cc2)cc1F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 2/20 0.34
SCN9A Q15858 1/20 0.33
FPR2 P25090 1/20 0.32
ALDH1A1 P00352 2/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PRKCE Q02156 1/20 0.31
PRKCQ Q04759 1/20 0.31
PRKCD Q05655 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
NAAA Q02083 1/20 0.31
HPGD P15428 1/20 0.31
AHR P35869 1/20 0.31
FFAR1 O14842 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766922 0.97 TUBB1 (0.35) TUBB1SCN9AFPR2ALDH1A1SMN1; SMN2
SCHEMBL14766803 0.94 TUBB1 (0.39) TUBB1SCN9AFPR2ALDH1A1SMN1; SMN2
SCHEMBL14766426 0.92 GABRA1 (0.33) TUBB1SCN9AALDH1A1GABRA1GABRB2
SCHEMBL14766684 0.92 GABRA1 (0.32) TUBB1SCN9AALDH1A1GABRA1GABRB2
SCHEMBL12739420 0.90 TUBB1 (0.34) TUBB1SCN9AFPR2ALDH1A1SMN1; SMN2
SCHEMBL14766508 0.90 TUBB1 (0.42) TUBB1FPR2NAAAHPGDFFAR1
SCHEMBL14766372 0.89 FPR2 (0.30) FPR2
SCHEMBL14765909 0.89 FPR2 (0.30) FPR2
SCHEMBL12739423 0.87 KDM4E (0.35) TUBB1SCN9AFPR2ALDH1A1SMN1; SMN2
SCHEMBL14767052 0.86 TUBB1 (0.34) TUBB1GABRA1GABRB2FFAR4NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed