SCHEMBL14766934

SCHEMBL14766934

CCOc1ccc(-c2ccc(C3CCC(COc4ccc(OCC)c(F)c4F)CC3)c(F)c2F)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 3/20 0.38
KCNH2 Q12809 2/20 0.38
ALOX5AP P20292 4/20 0.36
FEN1 P39748 4/20 0.36
FFAR4 Q5NUL3 2/20 0.35
PDE4D Q08499 1/20 0.35
FPR2 P25090 3/20 0.34
KDM1A O60341 1/20 0.34
FFAR1 O14842 1/20 0.34
PPARD Q03181 1/20 0.34
PTGIR P43119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766305 1.00 SSTR5 (0.38) SSTR5KCNH2ALOX5APFEN1FFAR4
SCHEMBL14765765 0.94 ALOX5AP (0.36) SSTR5KCNH2ALOX5APFEN1FFAR4
SCHEMBL14765746 0.94 ALOX5AP (0.36) SSTR5KCNH2ALOX5APFEN1FFAR4
SCHEMBL14766314 0.93 FPR2 (0.37) ALOX5APFEN1PDE4DFPR2FFAR1
SCHEMBL12823874 0.93 FPR2 (0.37) ALOX5APFEN1PDE4DFPR2FFAR1
SCHEMBL14765817 0.93 FPR2 (0.37) ALOX5APFEN1FFAR4FPR2FFAR1
SCHEMBL429829 0.91 SSTR5 (0.37) SSTR5KCNH2ALOX5APFEN1FFAR4
SCHEMBL10091340 0.91 SSTR5 (0.37) SSTR5KCNH2ALOX5APFEN1FFAR4
SCHEMBL14766561 0.91 FFAR1 (0.43) SSTR5KCNH2FFAR4PDE4DKDM1A
SCHEMBL12733566 0.91 ALOX5AP (0.36) SSTR5KCNH2ALOX5APFEN1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed