SCHEMBL14765817

SCHEMBL14765817

CCOc1ccc(-c2ccc(C3CCC(c4ccc(OCC)c(F)c4F)CC3)c(F)c2F)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 2/20 0.37
ALOX5AP P20292 3/20 0.37
FEN1 P39748 3/20 0.37
NQO1 P15559 1/20 0.37
FFAR4 Q5NUL3 2/20 0.37
FGFR1 P11362 1/20 0.36
FGFR2 P21802 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 1/20 0.35
FFAR1 O14842 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
NLRP3 Q96P20 1/20 0.34
SENP7 Q9BQF6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766934 0.93 SSTR5 (0.38) FPR2ALOX5APFEN1FFAR4FFAR1
SCHEMBL14766305 0.93 SSTR5 (0.38) FPR2ALOX5APFEN1FFAR4FFAR1
SCHEMBL13586297 0.92 ALOX5AP (0.40) FPR2ALOX5APFEN1FGFR1FGFR2
SCHEMBL14765827 0.90 NAAA (0.38) FPR2ALOX5APFEN1FFAR4FGFR1
SCHEMBL14766585 0.90 NAAA (0.38) FPR2ALOX5APFEN1FFAR4FGFR1
SCHEMBL14765807 0.90 HTR2C (0.36) FPR2ALOX5APFEN1FFAR4CYP2D6
SCHEMBL12733879 0.90 ALOX5AP (0.39) FPR2ALOX5APFEN1FGFR1FGFR2
SCHEMBL14765801 0.89 KDM1A (0.44) FPR2FFAR4FFAR1
SCHEMBL10164629 0.88 FPR2 (0.36) FPR2ALOX5APFEN1FFAR4FGFR1
SCHEMBL12733860 0.88 FEN1 (0.37) FPR2ALOX5APFEN1FFAR4FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed