Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 6/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766491 | 0.97 | SCN9A (0.36) | SCN9ADRD4SIGMAR1GABRA1GABRB2 | |
| SCHEMBL14766398 | 0.93 | SCN9A (0.39) | SCN9ADRD4SIGMAR1NAAATMEM97 | |
| SCHEMBL14766790 | 0.91 | GABRA1 (0.35) | GABRA1GABRB2NAAACNR2HTR6 | |
| SCHEMBL14766852 | 0.90 | GABRA1 (0.36) | SCN9ADRD4SIGMAR1GABRA1GABRB2 | |
| SCHEMBL12740253 | 0.90 | KDM4E (0.37) | SCN9ADRD4SIGMAR1GABRA1GABRB2 | |
| SCHEMBL14767246 | 0.90 | DRD4 (0.36) | SCN9ADRD4SIGMAR1GABRA1GABRB2 | |
| SCHEMBL14766400 | 0.90 | DRD4 (0.37) | SCN9ADRD4SIGMAR1NAAATMEM97 | |
| SCHEMBL14766496 | 0.90 | SCN9A (0.38) | SCN9ADRD4SIGMAR1NAAATMEM97 | |
| SCHEMBL14766624 | 0.89 | GLA (0.32) | SCN9AGABRA1GABRB2CNR2S1PR2 | |
| SCHEMBL14767113 | 0.89 | GABRA1 (0.36) | SCN9AGABRA1GABRB2NAAACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |