Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766823 | 0.94 | SCN9A (0.38) | KMT2ATHRATHRBSCN9AKCNQ3 | |
| SCHEMBL12741155 | 0.93 | KMT2A (0.34) | KMT2ATHRATHRBSCN9AKCNQ3 | |
| SCHEMBL14766783 | 0.92 | KDM4E (0.38) | KMT2ATHRATHRBKCNQ3KCNQ2 | |
| SCHEMBL14767022 | 0.91 | THRA (0.38) | KMT2ATHRATHRBSCN9AKCNQ3 | |
| SCHEMBL12823872 | 0.89 | IDO1 (0.32) | KMT2AKCNQ3KCNQ2KDM4ECYP2D6 | |
| SCHEMBL14767210 | 0.89 | KCNQ3 (0.41) | KMT2ATHRATHRBKCNQ3KCNQ2 | |
| SCHEMBL12741160 | 0.89 | KDM4E (0.34) | KMT2ATHRATHRBSCN9AKDM4E | |
| SCHEMBL12823631 | 0.88 | IDO1 (0.32) | KMT2ATHRATHRBSCN9AKCNQ3 | |
| SCHEMBL14767060 | 0.88 | FFAR4 (0.35) | FFAR4HCRTR2 | |
| SCHEMBL12741407 | 0.88 | SCN1A (0.34) | KMT2AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |