Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767249 | 0.92 | KMT2A (0.34) | KDM4EKMT2AKCNQ3KCNQ2THRA | |
| SCHEMBL12741152 | 0.91 | KDM4E (0.36) | KDM4EKMT2AMETHTR2CHTR2A | |
| SCHEMBL14767210 | 0.90 | KCNQ3 (0.41) | KMT2AKCNQ3KCNQ2THRATHRB | |
| SCHEMBL12823091 | 0.88 | POLB (0.34) | KDM4EKMT2AMETHTR2CHTR2A | |
| SCHEMBL14767152 | 0.87 | GYS1 (0.36) | KDM4ETSHRPOLBMAPK1NPC1 | |
| SCHEMBL14767020 | 0.87 | GYS1 (0.38) | KDM4EKMT2APOLBNPC1RAB9A | |
| SCHEMBL14767022 | 0.87 | THRA (0.38) | KMT2AKCNQ3KCNQ2THRATHRB | |
| SCHEMBL12741399 | 0.87 | SCN1A (0.35) | KDM4EKMT2AMETHTR2CHTR2A | |
| SCHEMBL14766151 | 0.87 | PDE4A (0.33) | KDM4EMETHTR2CHTR2AHTR2B | |
| SCHEMBL12741126 | 0.87 | KCNQ3 (0.38) | KMT2AKCNQ3KCNQ2SERPINE1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |