Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1622894 | 0.80 | ABCB1 (0.62) | ABCB1LMNANPC1RAB9ALIMK1 | |
| SCHEMBL23975874 | 0.80 | MAPK1 (0.43) | ABCB1LMNANPC1RAB9ALIMK1 | |
| SCHEMBL1622072 | 0.80 | ABCB1 (0.62) | ABCB1LMNANPC1RAB9ALIMK1 | |
| SCHEMBL6015563 | 0.79 | ABCB1 (0.42) | ABCB1LMNANPC1RAB9AMAPK1 | |
| SCHEMBL13982474 | 0.79 | ABCB1 (0.39) | ABCB1LMNANPC1RAB9AMAPK1 | |
| SCHEMBL6015560 | 0.77 | ABCB1 (0.59) | ABCB1LMNANPC1RAB9ALIMK1 | |
| SCHEMBL6015570 | 0.76 | ABCB1 (0.57) | ABCB1LMNANPC1RAB9ALIMK1 | |
| SCHEMBL1622881 | 0.74 | ABCB1 (0.56) | ABCB1LMNANPC1RAB9ALIMK1 | |
| SCHEMBL1622598 | 0.74 | ABCB1 (0.59) | ABCB1LMNANPC1RAB9ALIMK1 | |
| SCHEMBL1622006 | 0.74 | ABCB1 (1.00) | ABCB1LMNANPC1RAB9ALIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| US-20170119032-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED | 2017-05-04 | — | — | US | disclosed |
| US-20170119032-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED | 2017-05-04 | — | — | US | disclosed |
| US-9603848-B2 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-9603848-B2 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| EP-2062050-B1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX INC (US) | 2016-05-18 | — | — | EP | disclosed |
| US-20120177584-A1 | SWEETENER COMPOSITIONS AND METHODS OF MAKING THEM | SENOMYX, INC. (US) | 2012-07-12 | — | — | US | disclosed |
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| US-8119821-B2 | Sweetener compositions and methods of making them | SENOMYX, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-8119821-B2 | Sweetener compositions and methods of making them | SENOMYX, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110224155-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX INC. (US) | 2011-09-15 | — | — | US | disclosed |
| US-20090292010-A1 | SWEETENER COMPOSITIONS AND METHODS OF MAKING THEM | SENOMYX, INC. | 2009-11-26 | — | — | US | disclosed |
| US-20090292010-A1 | SWEETENER COMPOSITIONS AND METHODS OF MAKING THEM | SENOMYX, INC. | 2009-11-26 | — | — | US | disclosed |
| WO-2008154221-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| US-20080306093-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-11 | — | — | US | disclosed |
| US-20080306093-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119032-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ABCB1 4534/4885LMNA 4834/4885NPC1 1783/4885 |
| US-20080306093-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | OR51E2, TAS2R50, TAS2R30 | ABCB1 4212/4885LMNA 4624/4885NPC1 3785/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ABCB1 4534/4885LMNA 4834/4885NPC1 1783/4885 |
| US-20120177584-A1 | SWEETENER COMPOSITIONS AND METHODS OF MAKING THEM | SI, TAS2R5, TASP1 | ABCB1 4361/4885LMNA 4869/4885NPC1 2083/4885 |
| US-20110224155-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | TAS2R30, TAS2R50, TAS2R1 | ABCB1 4315/4885LMNA 4723/4885NPC1 2949/4885 |
| US-20090292010-A1 | SWEETENER COMPOSITIONS AND METHODS OF MAKING THEM | SI, TAS2R5, TASP1 | ABCB1 4361/4885LMNA 4869/4885NPC1 2083/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ABCB1 4534/4885LMNA 4834/4885NPC1 1783/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ABCB1 4534/4885LMNA 4834/4885NPC1 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.