Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2415732 | 0.75 | HTR5A (0.39) | HSD17B10GAAHTR5ASLC40A1ALDH1A1 | |
| SCHEMBL14767764 | 0.67 | — | — | |
| SCHEMBL20486488 | 0.59 | L3MBTL1 (0.39) | KMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL17705652 | 0.59 | ALDH1A1 (0.48) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL11645367 | 0.59 | KDM4E (0.57) | MEN1KMT2AGAAHTR2BMAPT | |
| SCHEMBL6015512 | 0.58 | HSP90AA1 (0.36) | MEN1KMT2AHSD17B10HTR5AMAPT | |
| SCHEMBL12896658 | 0.58 | RET (0.54) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL5822145 | 0.57 | TOP1 (0.43) | MEN1KMT2AHTR5AMAPTALDH1A1 | |
| SCHEMBL8286607 | 0.57 | CA12 (0.53) | MEN1KMT2AHSD17B10GAAHTR5A | |
| SCHEMBL18726136 | 0.56 | KMT2A (0.46) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2568287-A2 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |