Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 12/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14346478 | 0.83 | TSHR (0.47) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL504457 | 0.82 | — | — | |
| Acrylic Acid SCHEMBL9805941 | 0.79 | TSHR (0.44) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL14533405 | 0.78 | TSHR (0.42) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL10647766 | 0.78 | TDP1 (0.49) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL21313125 | 0.77 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL587102 | 0.77 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL9704499 | 0.77 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1389549 | 0.77 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL5098395 | 0.77 | TSHR (0.54) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242103-A | Methyl methacrylate-containing composition and method for producing methyl methacrylate polymer | 三菱化学株式会社 | 2023-12-15 | — | — | CN | disclosed |
| US-9668946-B2 | Dental materials based on monomers having debonding-on-demand properties | IVOCLAR VIVADENT AG (LI) | 2017-06-06 | — | — | US | disclosed |
| US-9668946-B2 | Dental materials based on monomers having debonding-on-demand properties | IVOCLAR VIVADENT AG (LI) | 2017-06-06 | — | — | US | disclosed |
| US-9668946-B2 | Dental materials based on monomers having debonding-on-demand properties | IVOCLAR VIVADENT AG (LI) | 2017-06-06 | — | — | US | disclosed |
| US-20140329929-A1 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2014-11-06 | — | — | US | disclosed |
| US-20140329929-A1 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2014-11-06 | — | — | US | disclosed |
| US-20140329929-A1 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2014-11-06 | — | — | US | disclosed |
| CN-103781456-A | Dental materials based on monomers having debonding-on-demand properties | IVOCLAR VIVADENT AG | 2014-05-07 | — | — | CN | disclosed |
| WO-2013034777-A2 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2013-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329929-A1 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | RCOR3, NR2E1, RER1 | TSHR 2377/4885THRB 1362/4885ALDH1A1 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.