Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 12/20 | 0.78 |
| ▸ | ADRA1B | P35368 | 12/20 | 0.78 |
| ▸ | ADRA1D | P25100 | 11/20 | 0.78 |
| ▸ | HTR7 | P34969 | 6/20 | 0.78 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.78 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.78 |
| ▸ | DRD4 | P21917 | 5/20 | 0.78 |
| ▸ | HRH2 | P25021 | 5/20 | 0.78 |
| ▸ | HRH1 | P35367 | 5/20 | 0.78 |
| ▸ | HTR2A | P28223 | 5/20 | 0.78 |
| ▸ | DRD2 | P14416 | 5/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.78 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.78 |
| ▸ | DRD3 | P35462 | 3/20 | 0.78 |
| ▸ | HTR5A | P47898 | 3/20 | 0.78 |
| ▸ | HTR6 | P50406 | 3/20 | 0.78 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.78 |
| ▸ | DRD1 | P21728 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4546517 | 0.89 | HTR1A (0.77) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| SCHEMBL4546509 | 0.88 | HTR1A (1.00) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| SCHEMBL16510265 | 0.88 | HTR1A (0.74) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| SCHEMBL4546507 | 0.83 | HTR1A (0.77) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| Fumaric Acid SCHEMBL8558915 | 0.82 | HTR1A (0.87) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| Fumaric Acid SCHEMBL8553731 | 0.82 | HTR1A (0.87) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| SCHEMBL12182133 | 0.81 | HTR1A (0.78) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| SCHEMBL12182153 | 0.79 | HTR1A (0.78) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| SCHEMBL15042722 | 0.79 | HTR1A (0.80) | HTR1AADRA1AADRA1BADRA1DHTR7 | |
| SCHEMBL8406618 | 0.79 | HTR1A (0.70) | HTR1AADRA1AADRA1BADRA1DHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130064770-A1 | RADIOLABELED COMPOUNDS AND METHODS THEREOF | GE HEALTHCARE LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130064770-A1 | RADIOLABELED COMPOUNDS AND METHODS THEREOF | HTR5A, HTR3B, HTR1A | HTR1A 3/4885ADRA1A 207/4885ADRA1B 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.