Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.34 |
| ▸ | PRKG1 | Q13976 | 5/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.34 |
| ▸ | PRKACA | P17612 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.34 |
| ▸ | PRKX | P51817 | 2/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.34 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.34 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699505 | 0.87 | TRPV1 (0.38) | CHRNA7ROCK2PRKG1ROCK1TRPV1 | |
| SCHEMBL1474347 | 0.87 | TRPV1 (0.38) | CHRNA7ROCK2PRKG1ROCK1TRPV1 | |
| SCHEMBL13685589 | 0.72 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL1474682 | 0.72 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL1476574 | 0.72 | KIF11 (0.41) | GSK3AGSK3BTRPV1CYP2C9 | |
| SCHEMBL13838875 | 0.72 | ROCK1 (0.39) | CHRNA7ROCK2PRKG1ROCK1RPS6KA5 | |
| SCHEMBL1476302 | 0.70 | TRPV1 (0.34) | TRPV1 | |
| SCHEMBL1474412 | 0.70 | TRPV1 (0.40) | CHRNA7TRPV1 | |
| SCHEMBL1474093 | 0.68 | CHRNA7 (0.46) | CHRNA7TRPV1 | |
| SCHEMBL1473593 | 0.66 | CHRNA7 (0.38) | CHRNA7TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915448-B2 | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists | PFIZER INC. (US) | 2011-03-29 | — | — | US | claimed |