Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12574770 | 0.86 | RAB9A (0.34) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14768892 | 0.86 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL12574775 | 0.84 | MAPT (0.35) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15032133 | 0.83 | MAPK8 (0.36) | L3MBTL1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL37478 | 0.83 | MAPK8 (0.36) | L3MBTL1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL14768894 | 0.83 | RAB9A (0.34) | RAB9ACNR2TSHR | |
| SCHEMBL14768897 | 0.82 | MAPK8 (0.35) | KDM4EALDH1A1KMT2AMAPK8 | |
| SCHEMBL15032127 | 0.75 | RXFP1 (0.35) | L3MBTL1MAPTRAB9AKMT2ANPC1 | |
| SCHEMBL12456817 | 0.74 | ALDH1A1 (0.35) | KDM4EALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL19139664 | 0.73 | POLB (0.35) | L3MBTL1KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | DDT, PKD2, PKD1 | L3MBTL1 2150/4885KDM4E 3242/4885ALDH1A1 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.