Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768894 | 0.93 | RAB9A (0.34) | POLBRAB9A | |
| SCHEMBL12456817 | 0.88 | ALDH1A1 (0.35) | ALDH1A1MAPTMAPK1POLBRAB9A | |
| SCHEMBL14768882 | 0.86 | L3MBTL1 (0.35) | ALDH1A1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL12574771 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MAPTMAPK1POLBRAB9A | |
| SCHEMBL12574767 | 0.83 | MAPT (0.34) | ALDH1A1MAPTMAPK1POLBRAB9A | |
| SCHEMBL37429 | 0.82 | RXFP1 (0.35) | — | |
| SCHEMBL1959599 | 0.81 | — | — | |
| SCHEMBL15032130 | 0.80 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL15032132 | 0.79 | MEN1 (0.35) | ALDH1A1MAPK1HPGDMEN1KMT2A | |
| SCHEMBL12574772 | 0.78 | RAB9A (0.36) | ALDH1A1MAPK1POLBRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | DDT, PKD2, PKD1 | ALDH1A1 154/4885MAPT 4692/4885MAPK1 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.