Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 13/20 | 0.47 |
| ▸ | CA1 | P00915 | 12/20 | 0.47 |
| ▸ | CA2 | P00918 | 12/20 | 0.47 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052197 | 0.86 | USP2 (0.59) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL15502054 | 0.85 | DNASE1L3 (0.53) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL13052196 | 0.85 | USP2 (0.56) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL14769031 | 0.85 | USP2 (0.52) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL12192035 | 0.84 | USP2 (0.69) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL14771584 | 0.84 | USP2 (0.52) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL14771585 | 0.83 | USP2 (0.59) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL12295575 | 0.83 | USP2 (0.63) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL14771619 | 0.83 | USP2 (0.56) | DNASE1L3PRMT1USP2L3MBTL1MEN1 | |
| SCHEMBL31344171 | 0.82 | USP2 (0.60) | DNASE1L3PRMT1USP2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051597-B2 | Fluorescent substrate for detection of enzymatic activity of nitrile-related enzyme | MITSUBISHI RAYON CO., LTD. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20140072990-A1 | FLUORESCENT SUBSTRATE FOR DETECTION OF ENZYMATIC ACTIVITY OF NITRILE-RELATED ENZYME | THE UNIVERSITY OF TOKYO (JP) | 2014-03-13 | — | — | US | disclosed |
| US-20130065263-A1 | FLUORESCENT SUBSTRATE FOR DETECTION OF ENZYMATIC ACTIVITY OF NITRILE-RELATED ENZYME | THE UNIVERSITY OF TOKYO (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065263-A1 | FLUORESCENT SUBSTRATE FOR DETECTION OF ENZYMATIC ACTIVITY OF NITRILE-RELATED ENZYME | DNPH1, NOS1, NAALAD2 | DNASE1L3 613/4885PRMT1 244/4885USP2 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.