Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6333321 | 0.98 | KDM4E (0.55) | KDM4EPOLBRECQLMAPTKMT2A | |
| Bromide SCHEMBL2482814 | 0.98 | KDM4E (0.59) | KDM4EPOLBRECQLMAPTKMT2A | |
| Iodide SCHEMBL29226832 | 0.98 | KDM4E (0.55) | KDM4EPOLBRECQLMAPTKMT2A | |
| Iodide SCHEMBL30920085 | 0.98 | KDM4E (0.56) | KDM4EPOLBRECQLMAPTKMT2A | |
| Iodide SCHEMBL1343656 | 0.98 | KDM4E (0.56) | KDM4EPOLBRECQLMAPTKMT2A | |
| SCHEMBL6332993 | 0.93 | KDM4E (0.51) | KDM4EPOLBRECQLMAPTKMT2A | |
| Butyric Acid SCHEMBL1362446 | 0.86 | KDM4E (0.72) | KDM4EPOLBRECQLMAPTKMT2A | |
| SCHEMBL9934703 | 0.86 | KDM4E (0.58) | KDM4EPOLBRECQLMAPTKMT2A | |
| SCHEMBL12201164 | 0.85 | KDM4E (0.62) | KDM4EPOLBRECQLMAPTKMT2A | |
| SCHEMBL6333000 | 0.84 | KDM4E (0.48) | KDM4EPOLBRECQLMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655132-B2 | Positive photosensitive lithographic printing plate | AGFA GRAPHICS NV (BE) | 2017-08-23 | — | — | EP | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| EP-1655132-B1 | Positive photosensitive lithographic printing plate | AGFA GRAPHICS NV (BE) | 2011-10-12 | — | — | EP | claimed |
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | claimed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | claimed |
| EP-2054012-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | Henkel AG & Co. KGaA (DE) | 2009-05-06 | — | — | EP | claimed |
| EP-1796627-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2009-03-04 | — | — | EP | claimed |
| US-7473280-B2 | Coloring agent compositions and methods of treating keratin fibers therewith | HENKEL KGAA (DE) | 2009-01-06 | — | — | US | claimed |
| US-20080189877-A1 | Mixture of quaternized imidazo[1,5-a]pyrimidinium derivate and benzaldehyde derivative; cationic hair dyes, oxidation color dyes; colorfastness, washfastness | HENKEL KGAA (DE) | 2008-08-14 | — | — | US | claimed |
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | claimed |
| WO-2006119818-A1 | AGENTS FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | claimed |
| EP-1433469-B1 | Composition for dyeing keratinous fibres | HENKEL KGAA (DE) | 2006-10-11 | — | — | EP | claimed |
| WO-2006077039-A1 | AGENTS FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-07-27 | — | — | WO | claimed |
| EP-1300134-B1 | Agent for dyeing keratinous fibres with isophthalaldehydes | HENKEL KGAA (DE) | 2006-04-26 | — | — | EP | claimed |
| WO-2006040015-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-04-20 | — | — | WO | claimed |
| WO-2006029687-A1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-03-23 | — | — | WO | claimed |
| WO-2006029672-A1 | PRODUCTS FOR DYEING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-03-23 | — | — | WO | claimed |
| EP-1263590-B1 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | KODAK POLYCHROME GRAPHICS CO (US) | 2005-03-16 | — | — | EP | claimed |
| EP-1143923-B1 | AGENT AND METHOD FOR COLOURING FIBRES | WELLA AG (DE) | 2004-05-06 | — | — | EP | claimed |
| US-4287335-A | WHEREIN SAID COMPOUND IS A STYRYLPYRIDINIUM SALT OR A STYRYLQUINOLINIUM SALT USEFUL IN PRODUCING A PHOTOSENSITIVE RESIN | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1981-09-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | KDM4E 1659/4885POLB 2891/4885RECQL 122/4885 |
| US-20080189877-A1 | Mixture of quaternized imidazo[1,5-a]pyrimidinium derivate and benzaldehyde derivative; cationic hair dyes, oxidation color dyes; colorfastness, washfastness | TYR, NDUFS5, WASHC5 | KDM4E 1235/4885POLB 293/4885RECQL 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.