Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476988 | 0.86 | KDM4E (0.57) | KDM4EPOLBRECQLMAPTKMT2A | |
| SCHEMBL8022993 | 0.85 | KDM4E (0.97) | KDM4EPOLBRECQLMAPTKMT2A | |
| Bromide SCHEMBL2482814 | 0.84 | KDM4E (0.59) | KDM4EPOLBRECQLMAPTKMT2A | |
| Iodide SCHEMBL1343656 | 0.84 | KDM4E (0.56) | KDM4EPOLBRECQLMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6333321 | 0.84 | KDM4E (0.55) | KDM4EPOLBRECQLMAPTKMT2A | |
| Iodide SCHEMBL30920085 | 0.84 | KDM4E (0.56) | KDM4EPOLBRECQLMAPTKMT2A | |
| Iodide SCHEMBL29226832 | 0.84 | KDM4E (0.55) | KDM4EPOLBRECQLMAPTKMT2A | |
| Bromide SCHEMBL8512189 | 0.84 | KDM4E (1.00) | KDM4EPOLBRECQLMAPTKMT2A | |
| Iodide SCHEMBL29210094 | 0.84 | KDM4E (0.94) | KDM4EPOLBRECQLMAPTKMT2A | |
| SCHEMBL16663887 | 0.82 | KDM4E (0.81) | KDM4EPOLBRECQLMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067602-B2 | Asymmetric cyanine fluorescent dyes, compositions and their use in staining biological samples | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2011-11-29 | — | — | US | disclosed |
| US-20090176270-A1 | ASYMMETRIC CYANINE FLUORESCENT DYES, COMPOSITIONS AND THEIR USE IN STAINING BIOLOGICAL SAMPLES | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176270-A1 | ASYMMETRIC CYANINE FLUORESCENT DYES, COMPOSITIONS AND THEIR USE IN STAINING BIOLOGICAL SAMPLES | IK, CRY1, CRY2 | KDM4E 2864/4885POLB 551/4885RECQL 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.