Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.63 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.63 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20438528 | 0.94 | FTO (0.57) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL20438529 | 0.92 | FTO (0.62) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL2083406 | 0.88 | FTO (0.63) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL5497717 | 0.88 | FTO (0.66) | FTOMAPTMEN1HTTKMT2A | |
| Alcohol SCHEMBL28868880 | 0.87 | FTO (0.62) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL1887860 | 0.87 | FTO (0.56) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL12275226 | 0.86 | FTO (0.72) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL20095 | 0.85 | FTO (0.69) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL29358729 | 0.85 | FTO (0.69) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL29838678 | 0.85 | FTO (0.69) | FTOMAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283630-B1 | OLIGONUCLEOTIDE FRAGMENT, AND METHOD AS WELL AS APPLICATION OF SELECTIVE AMPLIFICTION OF VARIANT OF TARGET NUCLEIC ACID SEQUENCE USING THE SAME | NUHIGH BIOTECHNOLOGIES CO LTD (CN) | 2023-07-26 | — | — | EP | disclosed |
| US-20210040553-A1 | OLIGONUCLEOTIDE FRAGMENT, AND METHOD AS WELL AS APPLICATION OF SELECTIVE AMPLIFICATION OF VARIANT OF TARGET NUCLEIC ACID SEQUENCE USING THE SAME | NUHIGH BIOTECHNOLOGIES CO LTD (CN) | 2021-02-11 | — | — | US | disclosed |
| US-20180030523-A1 | OLIGONUCLEOTIDE FRAGMENT, AND METHOD AS WELL AS APPLICATION OF SELECTIVE AMPLIFICATION OF VARIANT OF TARGET NUCLEIC ACID SEQUENCE USING THE SAME | Nuhigh Biotechnologies Co. Ltd. (CN) | 2018-02-01 | — | — | US | disclosed |
| US-20170227545-A1 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-08-10 | — | — | US | disclosed |
| WO-2016165210-A1 | OLIGONUCLEOTIDE FRAGMENT, AND METHOD AS WELL AS APPLICATION OF SELECTIVE AMPLIFICTION OF VARIANT OF TARGET NUCLEIC ACID SEQUENCE USING THE SAME | NUHIGH BIOTECHNOLOGIES CO.LTD. (CN) | 2016-10-20 | — | — | WO | disclosed |
| WO-2015191789-A2 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-12-17 | — | — | WO | disclosed |
| US-8753831-B2 | Methods for detection of botulinum neurotoxin | CITY OF HOPE (US) | 2014-06-17 | — | — | US | disclosed |
| US-20130065259-A1 | METHODS FOR DETECTION OF BOTULINUM NEUROTOXIN | CITY OF HOPE (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170227545-A1 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | NQO1, NCL, NANS | FTO 4100/4885MAPT 4575/4885MEN1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.