SCHEMBL1887860

SCHEMBL1887860

CCCCCCCCCCCCCCCC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 9/20 0.56
▸ MAPT P10636 2/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ HPGD P15428 1/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ RECQL P46063 1/20 0.56
▸ BLM P54132 1/20 0.56
▸ SMAD3 P84022 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ PRMT1 Q99873 1/20 0.56
▸ ACE2 Q9BYF1 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ HSD17B3 P37058 6/20 0.48
▸ KCNH2 Q12809 1/20 0.46
▸ ALB P02768 1/20 0.45
▸ CYP3A4 P08684 1/20 0.43
▸ GSTP1 P09211 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13593607 0.93 FTO (0.55) FTOMAPTMEN1HPGDCYP2C19
SCHEMBL14769914 0.87 FTO (0.63) FTOMAPTMEN1HPGDCYP2C19
Hexanoate SCHEMBL14157140 0.86 FTO (0.54) FTOMAPTMEN1HPGDCYP2C19
Fluorescein SCHEMBL27939701 0.83 FTO (0.69) FTOMAPTMEN1HPGDCYP2C19
Fluorescein SCHEMBL5886626 0.83 FTO (0.69) FTOMAPTMEN1HPGDCYP2C19
Fluorescein SCHEMBL14776969 0.83 FTO (0.69) FTOMAPTMEN1HPGDCYP2C19
Fluorescein SCHEMBL20764877 0.83 FTO (0.69) FTOMAPTMEN1HPGDCYP2C19
Fluorescein SCHEMBL19128333 0.83 FTO (0.69) FTOMAPTMEN1HPGDCYP2C19
SCHEMBL701402 0.83 FTO (0.69) FTOMAPTMEN1HPGDCYP2C19
SCHEMBL700563 0.83 FTO (0.69) FTOMAPTMEN1HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110104781-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2011-05-05 — — US claimed
US-20100233782-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2010-09-16 — — US claimed
EP-2118129-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2009-11-18 — — EP claimed
US-20090161828-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES LIFE TECHNOLOGIES (US) 2009-06-25 — — US claimed
US-20080248565-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES INVITROGEN CORPORATION (US) 2008-10-09 — — US claimed
WO-2008106660-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES INVITROGEN CORPORATION (US) 2008-09-04 — — WO claimed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 — — WO disclosed
US-20170298380-A1 IMIDAZOLINONE HERBICIDE RESISTANT BORAGE BIORIGINAL FOOD & SCIENCE CORP. (CA) 2017-10-19 — — US disclosed
US-20110104781-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2011-05-05 — — US disclosed
US-20100233782-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2010-09-16 — — US disclosed
EP-2118129-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2009-11-18 — — EP disclosed
US-20090161828-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES LIFE TECHNOLOGIES (US) 2009-06-25 — — US disclosed
US-20080248565-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES INVITROGEN CORPORATION (US) 2008-10-09 — — US disclosed
WO-2008106660-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES INVITROGEN CORPORATION (US) 2008-09-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170298380-A1 IMIDAZOLINONE HERBICIDE RESISTANT BORAGE HARS1, HACL2, AHSA1 FTO 2907/4885MAPT 4807/4885MEN1 4150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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