Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770586 | 0.94 | ALOX5 (0.39) | ALOX5PRKDCCCNCCDK8 | |
| SCHEMBL21184183 | 0.86 | ALOX5 (0.43) | ALOX5MAOAMAOBACHEPRKDC | |
| SCHEMBL14770564 | 0.85 | MAOA (0.37) | MAOAMAOBACHECYP2D6 | |
| SCHEMBL14770567 | 0.85 | MAOA (0.37) | MAOAMAOBACHECYP2D6 | |
| SCHEMBL9890191 | 0.85 | MAOA (0.42) | MAOAMAOBACHECYP2D6 | |
| SCHEMBL5029897 | 0.84 | ALOX5 (0.43) | ALOX5PRKDCCCNCCDK8 | |
| SCHEMBL5028377 | 0.83 | MAOA (0.39) | MAOAMAOBACHECYP2D6 | |
| SCHEMBL17166769 | 0.82 | ALOX5 (0.37) | ALOX5PRKDC | |
| SCHEMBL14949502 | 0.81 | ALOX5 (0.39) | ALOX5MAOAMAOBACHEPRKDC | |
| SCHEMBL5029698 | 0.81 | ALOX5 (0.46) | ALOX5CYP2D6PRKDCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | ALOX5 1836/4885MAOA 458/4885MAOB 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.