Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 7/20 | 0.32 |
| ▸ | GABRD | O14764 | 7/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.32 |
| ▸ | GABRE | P78334 | 7/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770616 | 1.00 | GABRP (0.32) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17679028 | 0.93 | JAK2 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14867964 | 0.92 | CHEK2 (0.34) | PTPRFPTPN2PTPN1 | |
| SCHEMBL14770562 | 0.92 | PTPRF (0.35) | PTPRFPTPN2PTPN1 | |
| SCHEMBL17678997 | 0.90 | JAK2 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14770611 | 0.90 | PLA2G2A (0.36) | PTPRFPTPN2PTPN1 | |
| SCHEMBL14770691 | 0.90 | PLA2G2A (0.36) | PTPRFPTPN2PTPN1 | |
| SCHEMBL14770637 | 0.89 | PTPRF (0.34) | PTPRFPTPN2PTPN1 | |
| SCHEMBL14770625 | 0.88 | MKNK1 (0.33) | PTPRFPTPN2PTPN1CYP1A2 | |
| SCHEMBL16452298 | 0.88 | CHEK2 (0.33) | PTPRFPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | GABRP 4276/4885GABRD 3433/4885GABRA1 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.