Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770664 | 0.96 | KDM4E (0.34) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14770734 | 0.96 | KDM4E (0.38) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14770702 | 0.96 | KDM4E (0.38) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14770667 | 0.94 | PLA2G2A (0.39) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10041333 | 0.94 | KDM4E (0.38) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2628368 | 0.93 | KDM4E (0.41) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14770662 | 0.92 | BTK (0.38) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14770665 | 0.92 | BTK (0.38) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14770554 | 0.91 | KDM4E (0.36) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2628346 | 0.91 | KDM4E (0.40) | KDM4ENPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | KDM4E 1763/4885NPC1 3134/4885MAPT 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.