Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.51 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343794 | 0.88 | MCL1 (0.78) | MCL1MAOBMAOASMN1; SMN2PTGS2 | |
| SCHEMBL27771284 | 0.87 | MAOB (0.66) | MCL1MAOBMAOASMN1; SMN2KLKB1 | |
| SCHEMBL25894138 | 0.87 | RXRA (0.61) | MCL1MAOBMAOAKLKB1CTSB | |
| SCHEMBL13973969 | 0.87 | MCL1 (0.60) | MCL1MAOBMAOASMN1; SMN2KLKB1 | |
| SCHEMBL14774262 | 0.87 | RAB9A (0.61) | MCL1MAOBMAOASMN1; SMN2KLKB1 | |
| SCHEMBL16704452 | 0.87 | MAOB (0.60) | MCL1MAOBMAOAKLKB1CTSB | |
| SCHEMBL13977571 | 0.87 | RXRA (0.61) | MCL1MAOBMAOASMN1; SMN2KLKB1 | |
| SCHEMBL3299304 | 0.85 | MCL1 (0.59) | MCL1MAOBMAOATSHRSMN1; SMN2 | |
| SCHEMBL13965427 | 0.84 | KAT8 (0.49) | MCL1MAOBMAOAKLKB1CTSB | |
| SCHEMBL13968250 | 0.83 | MCL1 (0.56) | MCL1MAOBMAOAKLKB1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065174-A1 | TONER | CANON KABUSHIKI KAISHA (JP) | 2013-03-14 | — | — | US | disclosed |