SCHEMBL14770871

SCHEMBL14770871

COc1cc2ccccc2cc1-c1cccn1C(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.49
HSP90AB1 P08238 1/20 0.49
PIK3R1 P27986 1/20 0.47
PIK3CA P42336 1/20 0.47
MET P08581 1/20 0.47
AXL P30530 1/20 0.47
MERTK Q12866 1/20 0.47
TNK2 Q07912 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ATR Q13535 1/20 0.38
NR1H2 P55055 6/20 0.38
BUB1 O43683 1/20 0.38
BCHE P06276 1/20 0.37
SUV39H2 Q9H5I1 2/20 0.37
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
NR1H3 Q13133 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19953372 0.91 HSP90AA1 (0.51) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL19718909 0.85 MET (0.47) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL14770848 0.84 HSP90AA1 (0.47) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL6040619 0.82 HSP90AA1 (0.44) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL22036737 0.81 HSP90AA1 (0.53) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL14770895 0.81 MAPT (0.49) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL28460770 0.80 HSP90AA1 (0.49) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL31518171 0.80 JAK2 (0.45) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL5991785 0.80 HSP90AA1 (0.44) HSP90AA1HSP90AB1PIK3R1PIK3CAMET
SCHEMBL14770874 0.79 HSP90AA1 (0.42) HSP90AA1HSP90AB1PIK3R1PIK3CAMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013035303-A1 ORGANIC THIN FILM SOLAR CELL MATERIAL 出光興産株式会社 (JP) 2013-03-14 WO disclosed