Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | CCR3 | P51677 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20082562 | 0.79 | ADORA2B (0.42) | CCR3 | |
| SCHEMBL17277305 | 0.78 | ROCK2 (0.40) | ROCK2CCR3GRM2TEAD1DRD2 | |
| SCHEMBL12075449 | 0.76 | CCR2 (0.39) | ROCK2CCR3GRM2TEAD1DRD2 | |
| SCHEMBL12062170 | 0.76 | ROCK2 (0.39) | ROCK2CCR3GRM2TEAD1 | |
| SCHEMBL17277490 | 0.73 | ROCK2 (0.46) | ROCK2 | |
| SCHEMBL12075870 | 0.72 | ROCK2 (0.45) | ROCK2 | |
| SCHEMBL14775 | 0.72 | TEAD1 (0.39) | ROCK2CCR3GRM2TEAD1DRD2 | |
| SCHEMBL12062105 | 0.71 | ADORA2B (0.35) | ROCK2CCR3GRM2HTR1ACYP2D6 | |
| SCHEMBL12075462 | 0.71 | ROCK2 (0.44) | ROCK2 | |
| SCHEMBL12062108 | 0.68 | ADORA2B (0.44) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047319-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |