Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775467 | 0.81 | CYP3A4 (0.45) | TSHRGAA | |
| SCHEMBL35874 | 0.79 | TSHR (0.44) | TSHRMEN1GAACYP2C9CYP2C19 | |
| Monoethanolamine SCHEMBL18530680 | 0.71 | PPARD (0.44) | TSHRMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL9442588 | 0.70 | TSHR (0.55) | TSHRMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL5050661 | 0.69 | MEN1 (0.63) | TSHRMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL19979585 | 0.69 | MEN1 (0.63) | TSHRMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL8463197 | 0.68 | GAA (0.45) | TSHRMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL14852884 | 0.67 | PPARD (0.44) | TSHRMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL15241266 | 0.67 | TSHR (0.50) | TSHRMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL9633264 | 0.66 | TSHR (0.55) | TSHRMEN1GAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149226-B2 | Preparation and use of aminoalkylphosphonic acid dialkyl ester compounds in a lubricant for antiwear, friction reduction, and/or micropitting prevention | AFTON CHEMICAL CORPORATION (US) | 2021-10-19 | — | — | US | disclosed |
| EP-2570471-B1 | Aminoalkylphosphonic acid dialkyl ester compounds in a lubricant for antiwear and/or friction reduction | AFTON CHEMICAL CORP (US) | 2021-04-07 | — | — | EP | disclosed |
| US-20200181522-A1 | Preparation and Use of Aminoalkylphosphonic Acid Dialkyl Ester Compounds in a Lubricant for Antiwear, Friction Reduction, and/or Micropitting Prevention | AFTON CHEMICAL CORP (US) | 2020-06-11 | — | — | US | disclosed |
| US-10563146-B2 | Preparation and use of aminoalkylphosphonic acid dilakyl ester compounds in a lubricant for antiwear, friction reduction, and/or micropitting prevention | AFTON CHEMICAL CORPORATION (US) | 2020-02-18 | — | — | US | disclosed |
| US-20130072407-A1 | PREPARATION AND USE OF AMINOALKYLPHOSPHONIC ACID DILAKYL ESTER COMPOUNDS IN A LUBRICANT FOR ANTIWEAR, FRICTION REDUCTION, AND/OR MICROPITTING PREVENTION | AFTON CHEMICAL CORPORATION (US) | 2013-03-21 | — | — | US | disclosed |
| EP-2570471-A1 | Preparation and use of aminoalkylphosphonic acid dialkyl ester compounds in a lubricant for antiwear and/or friction reduction | Afton Chemical Corporation (US) | 2013-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072407-A1 | PREPARATION AND USE OF AMINOALKYLPHOSPHONIC ACID DILAKYL ESTER COMPOUNDS IN A LUBRICANT FOR ANTIWEAR, FRICTION REDUCTION, AND/OR MICROPITTING PREVENTION | TP53RK, MDK, DEK | TSHR 3509/4885MEN1 4353/4885GAA 3860/4885 |
| US-11149226-B2 | Preparation and use of aminoalkylphosphonic acid dialkyl ester compounds in a lubricant for antiwear, friction reduction, and/or micropitting prevention | TP53RK, PHOSPHO1, PTAFR | TSHR 2938/4885MEN1 4516/4885GAA 4016/4885 |
| US-20200181522-A1 | Preparation and Use of Aminoalkylphosphonic Acid Dialkyl Ester Compounds in a Lubricant for Antiwear, Friction Reduction, and/or Micropitting Prevention | TP53RK, PHOSPHO1, PTAFR | TSHR 2938/4885MEN1 4516/4885GAA 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.