Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35874 | 0.89 | TSHR (0.44) | PPARDTSHRMEN1KMT2AGAA | |
| SCHEMBL1477184 | 0.73 | PPARD (0.45) | PPARDTSHRGAATDP1 | |
| SCHEMBL14775210 | 0.71 | TSHR (0.44) | PPARDTSHRMEN1KMT2AGAA | |
| SCHEMBL7086754 | 0.70 | TSHR (0.56) | PPARDTSHRMEN1KMT2AGAA | |
| SCHEMBL14852884 | 0.70 | PPARD (0.44) | PPARDTSHRMEN1KMT2AGAA | |
| SCHEMBL8463197 | 0.68 | GAA (0.45) | PPARDTSHRMEN1KMT2AGAA | |
| SCHEMBL19979584 | 0.67 | CYP2C9 (0.56) | PPARDTSHRMEN1KMT2AGAA | |
| SCHEMBL530398 | 0.67 | CYP2C9 (0.56) | PPARDTSHRMEN1KMT2AGAA | |
| SCHEMBL4584399 | 0.66 | TSHR (0.52) | PPARDTSHRMEN1KMT2AGAA | |
| SCHEMBL13631391 | 0.66 | MEN1 (0.50) | PPARDTSHRMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029337-A1 | FLAME-RESISTANT POLYMER POLYOL DISPERSION | PCC ROKITA SA (PL) | 2017-02-23 | — | — | WO | disclosed |