Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.38 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.38 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.38 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.38 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895833 | 0.91 | HRH1 (0.66) | HRH1ROCK1IKBKBHRH3ROCK2 | |
| SCHEMBL21281 | 0.86 | PARP10 (0.44) | HRH1HRH3PARP10 | |
| SCHEMBL2924302 | 0.84 | PARP10 (0.43) | HRH1HRH3PARP10 | |
| SCHEMBL676960 | 0.84 | PARP10 (0.43) | HRH1HRH3PARP10 | |
| SCHEMBL22392 | 0.84 | PARP10 (0.43) | HRH1HRH3PARP10 | |
| SCHEMBL27560412 | 0.82 | PARP10 (0.42) | HRH1HRH3PARP10 | |
| SCHEMBL231982 | 0.82 | PARP10 (0.48) | HRH1HRH3PARP10SLC6A2SLC6A3 | |
| SCHEMBL4875434 | 0.81 | CHRNB2 (0.53) | HRH1ROCK1ROCK2PRKACAPRKG1 | |
| SCHEMBL6529789 | 0.79 | PARP10 (0.41) | HRH1HRH3PARP10 | |
| SCHEMBL333383 | 0.78 | HRH1 (0.43) | HRH1HRH3PARP10SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |