Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27675564 | 0.73 | GPBAR1 (0.37) | SORDGPBAR1GPR119 | |
| SCHEMBL9893053 | 0.73 | SORD (0.37) | SORDGRM1GPBAR1CHRM1GPR119 | |
| SCHEMBL16480435 | 0.67 | GRM1 (0.43) | SORDGRM1GPR119CHRM4RPS6KA5 | |
| SCHEMBL9108658 | 0.67 | GAA (0.45) | SORDGRM1CHRM1GPR119 | |
| SCHEMBL28187889 | 0.66 | GPR119 (0.47) | SORDGRM1GPBAR1CHRM1AKT1 | |
| Hydrochloric Acid SCHEMBL27675360 | 0.66 | SORD (0.35) | SORDGRM1GPBAR1AKT1GPR119 | |
| SCHEMBL29200857 | 0.66 | GRM1 (0.37) | SORDGRM1GPBAR1CHRM1AKT1 | |
| SCHEMBL30475254 | 0.66 | GRM1 (0.37) | SORDGRM1GPBAR1CHRM1AKT1 | |
| SCHEMBL28004627 | 0.65 | GPR119 (0.52) | SORDGRM1GPBAR1CHRM1AKT1 | |
| Hydrochloric Acid SCHEMBL27675481 | 0.65 | GPBAR1 (0.44) | SORDGRM1GPBAR1AKT1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342191-B1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-03-20 | — | — | EP | disclosed |