Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CEL | P19835 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | ARF6 | P62330 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688565 | 0.83 | PARP1 (0.45) | PARP1MAOAMAOBPPOXKDM4E | |
| SCHEMBL2662415 | 0.72 | MAOA (0.43) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL2653820 | 0.71 | KDM4E (0.42) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL454553 | 0.70 | PPOX (0.52) | PARP1MAOAMAOBPPOXKDM4E | |
| SCHEMBL3949015 | 0.69 | PARP1 (0.35) | PARP1MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL2653647 | 0.69 | CYP3A4 (0.42) | PARP1MAOAMAOBALDH1A1HPGD | |
| SCHEMBL28641724 | 0.69 | CES1 (0.50) | PARP1MAOAMAOBPPOXKDM4E | |
| SCHEMBL6154703 | 0.67 | CES1 (0.55) | PARP1MAOAMAOBPPOXKDM4E | |
| SCHEMBL9450352 | 0.67 | PPOX (0.48) | PARP1MAOAMAOBPPOXALDH1A1 | |
| SCHEMBL28688078 | 0.67 | PPOX (0.48) | PARP1MAOAMAOBPPOXKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233512-B1 | POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF | NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) | 2013-03-20 | — | — | EP | claimed |