Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 7/20 | 0.39 |
| ▸ | PLK4 | O00444 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | LYN | P07948 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386018 | 0.73 | SMN1; SMN2 (0.61) | ALDH1A1MAPTTSHRCLK4KIF11 | |
| SCHEMBL16897359 | 0.72 | HDAC3 (0.58) | ALDH1A1MAPTHSD17B10KDRPLK4 | |
| SCHEMBL2231313 | 0.72 | ALDH1A1 (0.47) | PRKCZALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11415508 | 0.72 | MAPT (0.61) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL544047 | 0.72 | BCAT2 (0.52) | PRKCZALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL2948840 | 0.71 | MEN1 (0.50) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL10778839 | 0.71 | SMN1; SMN2 (0.52) | MAPTKMT2ATSHRHSD17B10CLK4 | |
| SCHEMBL3038302 | 0.69 | MAPT (0.70) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7459057 | 0.69 | RAB9A (0.46) | PRKCZALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11405284 | 0.69 | SMN1; SMN2 (0.50) | MAPTKMT2ATSHRHSD17B10CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991226-B1 | INHIBITORS OF HISTONE DEACETYLASE | MERCK SHARP & DOHME (US) | 2013-03-20 | — | — | EP | disclosed |