Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208429 | 0.82 | PTGS1 (0.56) | PTGS1PTGS2MTNR1APIM1ALOX5 | |
| SCHEMBL31560396 | 0.78 | PTGS1 (0.49) | PTGS1PTGS2MTNR1APIM1ALOX5 | |
| SCHEMBL14775704 | 0.77 | MEN1 (0.51) | PTGS1PTGS2MAOB | |
| SCHEMBL14775630 | 0.77 | ALOX5 (0.49) | PTGS1PTGS2MTNR1AALOX5ALOX12 | |
| SCHEMBL7147930 | 0.73 | PTGS2 (0.70) | PTGS1PTGS2 | |
| SCHEMBL7150875 | 0.73 | PTGS2 (0.70) | PTGS1PTGS2 | |
| SCHEMBL7150887 | 0.73 | ALOX5 (0.48) | PTGS1PTGS2ALOX5MAOB | |
| SCHEMBL10702114 | 0.72 | ALOX5 (0.57) | PTGS1PTGS2MTNR1AALOX5MAOB | |
| SCHEMBL1211173 | 0.72 | PTGS1 (0.42) | PTGS1PTGS2MTNR1AALOX5MAOB | |
| SCHEMBL2054544 | 0.72 | PTGS1 (0.42) | PTGS1PTGS2MTNR1AALOX5ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240467-B1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | EVOTEC AG (DE) | 2013-03-20 | — | — | EP | claimed |