Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186906 | 0.89 | SMN1; SMN2 (0.49) | PDCD1CD274MEN1KMT2AMMP8 | |
| SCHEMBL1780144 | 0.89 | SMN1; SMN2 (0.49) | PDCD1CD274MEN1KMT2AMMP8 | |
| SCHEMBL1781525 | 0.89 | SMN1; SMN2 (0.49) | PDCD1CD274MEN1KMT2AMMP8 | |
| SCHEMBL14776768 | 0.89 | MEN1 (0.49) | PDCD1CD274MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL7323482 | 0.88 | SMN1; SMN2 (0.48) | PDCD1CD274MEN1KMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL3366422 | 0.88 | SMN1; SMN2 (0.48) | PDCD1CD274MEN1KMT2AMMP8 | |
| SCHEMBL29176922 | 0.84 | CD274 (0.49) | PDCD1CD274MEN1KMT2AAOC3 | |
| SCHEMBL10519227 | 0.78 | PPID (0.43) | PDCD1CD274MEN1KMT2A | |
| SCHEMBL1839763 | 0.78 | ATM (0.55) | MEN1KMT2A | |
| SCHEMBL7856109 | 0.78 | ATM (0.55) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072722-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-03-21 | — | — | US | claimed |
| US-20130072722-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072722-A1 | SUPPORTED METAL CATALYSTS | SOD1, HNMT, SOD3 | PDCD1 984/4885CD274 1106/4885MEN1 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.