Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22500751 | 0.98 | LMNA (0.41) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| Bromide SCHEMBL14779567 | 0.96 | LMNA (0.39) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| Iodide SCHEMBL14778058 | 0.96 | LMNA (0.39) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL22500789 | 0.96 | LMNA (0.42) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL22500701 | 0.96 | SMN1; SMN2 (0.39) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL3814229 | 0.94 | SMN1; SMN2 (0.40) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL22501068 | 0.90 | LMNA (0.46) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL22500693 | 0.90 | ALDH1A1 (0.36) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| SCHEMBL3812431 | 0.88 | ALDH1A1 (0.38) | LMNAALDH1A1KMT2AHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL14778041 | 0.86 | LMNA (0.36) | LMNAALDH1A1KMT2AHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658842-B2 | Process for producing ethylene glycol catalyzed by ionic liquid | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2014-02-25 | — | — | US | disclosed |
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072727-A1 | PROCESS FOR PRODUCING ETHYLENE GLYCOL CATALYZED BY IONIC LIQUID | AGL, ALKBH3, ELL | LMNA 1421/4885ALDH1A1 1764/4885KMT2A 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.