SCHEMBL14780550

SCHEMBL14780550

CCC(C)(CC)S(=O)(=O)c1ccc(-c2ccc(OC)nc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.47
MKNK1 Q9BUB5 1/20 0.47
MKNK2 Q9HBH9 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
OXTR P30559 1/20 0.43
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
CYP2A6 P11509 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
PTGES2 Q9H7Z7 1/20 0.41
PDGFRB P09619 1/20 0.39
PDGFRA P16234 1/20 0.39
ALPL P05186 1/20 0.38
ERN1 O75460 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14780559 0.79 PKM (0.48) PTGS1PTGS2
SCHEMBL1422276 0.76 CA2 (0.72) KCNH2MKNK1MKNK2CA1CA2
SCHEMBL1422416 0.74 KCNH2 (0.72) KCNH2MKNK1MKNK2CA1CA2
SCHEMBL31174412 0.73 CYP2A6 (0.68) MKNK1MKNK2CA1CA2HSD17B1
SCHEMBL3754419 0.73 CYP2A6 (0.68) MKNK1MKNK2CA1CA2HSD17B1
SCHEMBL14780551 0.72 CA12 (0.55) CA1CA2
SCHEMBL14780552 0.72 CA1 (0.55) CA1CA2PTGS2
SCHEMBL1622275 0.71 MKNK1 (0.54) MKNK1MKNK2HSD17B1HSD17B2CYP2A6
SCHEMBL13618882 0.71 MKNK1 (0.54) MKNK1MKNK2HSD17B1HSD17B2CYP2A6
SCHEMBL131058 0.69 NAAA (0.49) KCNH2MKNK1MKNK2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399136-B2 Electrolyte solution for lithium ion secondary battery, lithium ion secondary battery, fluoroalkane derivative and gelling agent ASAHI KASEI E-MATERIALS CORPORATION (JP) 2013-03-19 US disclosed