Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309597 | 0.96 | THRB (0.45) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL12866520 | 0.94 | THRB (0.52) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL16804047 | 0.89 | THRB (0.60) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL6292051 | 0.89 | THRB (0.60) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL7631129 | 0.89 | THRB (0.60) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL19770675 | 0.89 | THRB (0.60) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL12281676 | 0.89 | THRB (0.60) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL16919771 | 0.89 | THRB (0.60) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL14464243 | 0.86 | THRB (0.53) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL14173110 | 0.86 | THRB (0.65) | THRBALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399569-B2 | Reactive urethane compound having ether bond, curable composition, and cured material | SHOWA DENKO K.K. (JP) | 2013-03-19 | — | — | US | disclosed |