Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783470 | 0.90 | MYC (0.40) | MYCKDM4EALDH1A1HPGDCFTR | |
| SCHEMBL2372871 | 0.89 | CFTR (0.45) | MYCKDM4EALDH1A1CFTRSMN1; SMN2 | |
| SCHEMBL2381481 | 0.86 | CFTR (0.42) | MYCKDM4EALDH1A1CFTRSMN1; SMN2 | |
| SCHEMBL17103826 | 0.85 | CFTR (0.42) | MYCKDM4EALDH1A1CFTRSMN1; SMN2 | |
| SCHEMBL2372346 | 0.84 | CFTR (0.42) | MYCKDM4EALDH1A1CFTRSMN1; SMN2 | |
| SCHEMBL2372480 | 0.82 | CFTR (0.40) | MYCKDM4EALDH1A1CFTRSMN1; SMN2 | |
| SCHEMBL2371652 | 0.81 | CFTR (0.39) | MYCKDM4EALDH1A1HPGDCFTR | |
| SCHEMBL2383885 | 0.80 | MYC (0.43) | MYCKDM4EALDH1A1CFTRSMN1; SMN2 | |
| SCHEMBL2372372 | 0.80 | MYC (0.43) | MYCKDM4EALDH1A1CFTRSMN1; SMN2 | |
| SCHEMBL29699381 | 0.79 | CFTR (0.45) | MYCKDM4EALDH1A1CFTRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013038378-A1 | Pyridine amide derivatives | NOVARTIS AG (CH) | 2013-03-21 | — | — | WO | disclosed |