Pyrrolidine

Pyrrolidine

SCHEMBL1478729

C1CCNC1.N.NC(=S)S

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.37
CXCR4 P61073 1/20 0.37
MAPT P10636 2/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
PMP22 Q01453 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
NOS2 P35228 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL157612 0.97
Piperidine SCHEMBL27755341 0.94 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2CXCR4MAPTHSD17B10
Piperidine SCHEMBL476425 0.94 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2CXCR4MAPTHSD17B10
Pyrrolidine SCHEMBL27968527 0.94 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CXCR4MAPTHSD17B10
Pyrrolidine SCHEMBL14815975 0.94 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CXCR4MAPTHSD17B10
Piperidine SCHEMBL27925102 0.94 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2CXCR4MAPTHSD17B10
Pyrrolidine SCHEMBL6930404 0.94 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CXCR4MAPTHSD17B10
Pyrrolidine SCHEMBL14815556 0.94 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CXCR4MAPTHSD17B10
Piperidine SCHEMBL1396086 0.94 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2CXCR4MAPTHSD17B10
Piperidine SCHEMBL27977836 0.92 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2CXCR4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119677765-A Method for producing antibiotic macrocyclic peptides 豪夫迈·罗氏有限公司 2025-03-21 CN claimed
CN-119314868-A Wafer cleaning liquid and semiconductor structure forming method 中芯国际集成电路制造(上海)有限公司 2025-01-14 CN claimed
CN-119290555-A Enrichment and detection method for trace mercury ions in water body 信阳师范大学 2025-01-10 CN claimed
CN-119297394-A Lithium battery electrolyte and preparation method and application thereof 扬州工业职业技术学院 2025-01-10 CN claimed
CN-119265287-A Sequencing reaction stabilizer composition and application thereof 深圳华大生命科学研究院 2025-01-07 CN claimed
US-20240182421-A1 SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2024-06-06 US claimed
CN-118016514-A Method for forming semiconductor device and cleaning liquid 中芯国际集成电路制造(上海)有限公司 2024-05-10 CN claimed
EP-4308109-A1 SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES Oregon Health & Science University (US) 2024-01-24 EP claimed
CN-117042768-A Synthesis of enodoxine-like quinolones 俄勒冈健康与科学大学 2023-11-10 CN claimed
CN-115684144-A Method for rapidly detecting arsenic content in water 广东环凯生物技术有限公司 2023-02-03 CN claimed
US-5723339-A COMPLEXING WITH AMMONIUM PYRROLIDINE DITHIOCARBAMATE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1998-03-03 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0560877-A4 METHOD AND APPARATUS TO DETOXIFY AQUEOUS BASED HAZARDOUS WASTE 1993-12-29 EP claimed
EP-0560877-A1 METHOD AND APPARATUS TO DETOXIFY AQUEOUS BASED HAZARDOUS WASTE CLEAN HARBORS, INC. (US) 1993-09-22 EP claimed
US-5221480-A Concurrent removal of various organics and heavy metals CLEAN HARBORS, INC. (US) 1993-06-22 US claimed
WO-1992010263-A1 METHOD AND APPARATUS TO DETOXIFY AQUEOUS BASED HAZARDOUS WASTE CLEAN HARBORS, INC. (US) 1992-06-25 WO claimed
US-5087370-A Method and apparatus to detoxify aqueous based hazardous waste CLEAN HARBORS, INC. (US) 1992-02-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182421-A1 SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES ENGASE, ESYT2, VPS4B ALDH1A1 3179/4885SMN1; SMN2 4828/4885CXCR4 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.