Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MMP9 | P14780 | 13/20 | 0.47 |
| ▸ | MMP2 | P08253 | 12/20 | 0.47 |
| ▸ | MMP8 | P22894 | 11/20 | 0.47 |
| ▸ | MMP13 | P45452 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14782938 | 1.00 | LMNA (0.57) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL14788950 | 0.98 | LMNA (0.59) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL14788925 | 0.92 | LMNA (0.61) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL4379822 | 0.85 | MMP9 (0.63) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL4390355 | 0.85 | MMP9 (0.63) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL712742 | 0.85 | MMP9 (0.63) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL4382583 | 0.85 | MMP9 (0.63) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL1641551 | 0.83 | MMP9 (0.61) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL918796 | 0.82 | LMNA (0.64) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL14782791 | 0.81 | LMNA (0.57) | LMNAMMP9MMP2MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013038153-A1 | 18F-LABELLED BARBITURATE COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2013-03-21 | — | — | WO | disclosed |