Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 11/20 | 0.42 |
| ▸ | MMP2 | P08253 | 10/20 | 0.42 |
| ▸ | MMP8 | P22894 | 10/20 | 0.42 |
| ▸ | MMP13 | P45452 | 10/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788950 | 0.94 | LMNA (0.59) | LMNAALDH1A1MMP9MMP2MMP8 | |
| SCHEMBL14782938 | 0.92 | LMNA (0.57) | LMNAALDH1A1MMP9MMP2MMP8 | |
| SCHEMBL14788924 | 0.92 | LMNA (0.57) | LMNAALDH1A1MMP9MMP2MMP8 | |
| SCHEMBL9694966 | 0.84 | LMNA (0.61) | LMNAALDH1A1MMP9MMP2MMP8 | |
| Butethal SCHEMBL44262 | 0.83 | LMNA (0.67) | LMNAALDH1A1MMP9MMP2MMP8 | |
| Hydrochloric Acid SCHEMBL9694949 | 0.82 | LMNA (0.59) | LMNAALDH1A1MMP9MMP2MMP8 | |
| Butethal SCHEMBL2718536 | 0.82 | LMNA (0.64) | LMNAALDH1A1MMP9MMP2MMP8 | |
| SCHEMBL918796 | 0.82 | LMNA (0.64) | LMNAALDH1A1MMP9MMP2MMP8 | |
| SCHEMBL4382583 | 0.80 | MMP9 (0.63) | LMNAALDH1A1MMP9MMP2MMP8 | |
| SCHEMBL4379822 | 0.80 | MMP9 (0.63) | LMNAALDH1A1MMP9MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013038153-A1 | 18F-LABELLED BARBITURATE COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2013-03-21 | — | — | WO | disclosed |