SCHEMBL147891

SCHEMBL147891

Cl[C](Cl)C(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27891621 0.96
SCHEMBL982602 0.80 ALDH1A1 (0.30)
SCHEMBL18242460 0.75
SCHEMBL5590971 0.75
SCHEMBL392318 0.75
SCHEMBL18243580 0.73 THRB (0.31) THRB
SCHEMBL12486837 0.73
SCHEMBL12486012 0.73
SCHEMBL5590764 0.72
SCHEMBL395093 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2779 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146383-A1 CYP11A1 INHIBITOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2024-07-11 WO claimed
CN-118307519-A CYP11A1 inhibitor compound, preparation method and application thereof 上海闻耐医药科技有限公司 2024-07-09 CN claimed
WO-2024104322-A1 15-PGDH INHIBITOR 武汉人福创新药物研发中心有限公司 2024-05-23 WO claimed
CN-118027058-A 15-PGDH inhibitors 武汉人福创新药物研发中心有限公司 2024-05-14 CN claimed
CN-117327000-A Biphenyl tetrahydropyrrole compound and preparation method and application thereof 海南因瑞生物医药科技有限公司 2024-01-02 CN claimed
CN-115232129-B PARP1 selective inhibitor and preparation method and application thereof 上海闻耐医药科技有限公司 2023-12-01 CN claimed
WO-2023141852-A1 CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF 益方生物科技(上海)股份有限公司 2023-08-03 WO claimed
CN-115232129-A PARP1 selective inhibitor and preparation method and application thereof 上海闻耐医药科技有限公司 2022-10-25 CN claimed
CN-110121488-B Process for producing halogenated alpha-fluoroethers 中央硝子株式会社 2022-04-12 CN claimed
US-8656638-B2 Compounds and processes that generate cyclopropenes and substituted cyclopropenes on demand STEVENSON CHERYL D (US) 2014-02-25 US claimed
US-20130281296-A1 Compunds and processes that generate cyclopropenes and substituted cyclopropenes on demand STEVENSON CHERYL D (US) 2013-10-24 US claimed
WO-2012128780-A1 COMPOUNDS AND PROCESSES THAT GENERATE CYCLOPROPENES AND SUBSTTITUTED CYCLOPROPENES ON DEMAND PRAGMACHEM LLC (US) 2012-09-27 WO claimed
US-20110232178-A1 Compounds and processes that generate cyclopropenes and substituted cyclopropenes on demand DAVIS JOHN PERRIN 2011-09-29 US claimed
CN-114805365-B Factor XIA new macrocycles carrying non-aromatic P2' groups 百时美施贵宝公司 2024-07-23 CN disclosed
CN-112055711-B Cyclohexylic acid triazolazine as LPA antagonist 百时美施贵宝公司 2024-07-23 CN disclosed
CN-116804005-B Kinesin KIF18A inhibitor and application thereof 上海湃隆生物科技有限公司 2024-07-19 CN disclosed
US-5162407-A Silicone rubber sealant composition INVESTORS DIVERSIFIED CAPITAL, INC. (US) 1992-11-10 US disclosed
US-4529687-A Low silver containing photographic material; developer is a nitrogen containing heterocyclic material FUJI PHOTO FILM CO., LTD. (JP) 1985-07-16 US disclosed
US-4156005-A ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS MERCK & CO., INC. (US) 1979-05-22 US disclosed
US-3976785-A Dioxocyclohexanecarboxanilide insecticides and acaricides AMERICAN CYANAMID COMPANY (US) 1976-08-24 US disclosed