⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31005279 | 0.78 | P2RX7 (0.40) | — | |
| SCHEMBL24579553 | 0.73 | P2RX7 (0.42) | — | |
| SCHEMBL3667124 | 0.73 | — | — | |
| SCHEMBL9395336 | 0.73 | P2RX7 (0.33) | — | |
| SCHEMBL6644100 | 0.69 | RAB9A (0.54) | — | |
| SCHEMBL27677548 | 0.69 | NAPRT (0.50) | — | |
| SCHEMBL18257235 | 0.69 | — | — | |
| SCHEMBL108190 | 0.69 | — | — | |
| SCHEMBL29087890 | 0.67 | P2RX7 (0.38) | — | |
| SCHEMBL1478693 | 0.67 | P2RX7 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388506-A | Pyrimidothiophene compound of 3-aminothiophene fragment, preparation method and application thereof | 贵州大学 | 2024-07-26 | — | — | CN | claimed |
| EP-2699606-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | Bridgestone Corporation (JP) | 2014-02-26 | — | — | EP | claimed |
| EP-2483317-B1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2014-02-26 | — | — | EP | claimed |
| US-20140018500-A1 | Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group | BRIDGESTONE CORPORATION (JP) | 2014-01-16 | — | — | US | claimed |
| WO-2012135451-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2012-10-04 | — | — | WO | claimed |
| EP-2483317-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-08-08 | — | — | EP | claimed |
| US-20120184677-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2012-07-19 | — | — | US | claimed |
| WO-2011041534-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-04-07 | — | — | WO | claimed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | claimed |
| EP-1465895-A2 | 4-OXO-4,7-DIHYDROFURO(2,3-B)PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-10-13 | — | — | EP | claimed |
| WO-2003059911-A2 | 4-OXO-4, 7-DIHYDROFURO[2,3-b]PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-24 | — | — | WO | claimed |
| WO-2025056007-A1 | FOUR-MEMBERED RING AMIDE COMPOUNDS AND USE THEREOF | 青岛清原化合物有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-118164997-B | Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof | 沈阳药科大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-118388506-A | Pyrimidothiophene compound of 3-aminothiophene fragment, preparation method and application thereof | 贵州大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-118164997-A | Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof | 沈阳药科大学 | 2024-06-11 | — | — | CN | disclosed |
| WO-2003059911-A2 | 4-OXO-4, 7-DIHYDROFURO[2,3-b]PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-24 | — | — | WO | disclosed |
| EP-0588194-A2 | Hydrazones and their use as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-23 | — | — | EP | disclosed |
| EP-0573837-A1 | Acetal-containing pyrimidinylthioaliphatic acid derivatives useful as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0571856-A1 | Pyrimidinylthioacrylic acid derivatives useful as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-12-01 | — | — | EP | disclosed |
| EP-0229283-A1 | Anilides of pyrimidyl-thio-carboxylic acids | BAYER AG (DE) | 1987-07-22 | — | — | EP | disclosed |