SCHEMBL3667124

SCHEMBL3667124

NC(=S)c1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31005279 0.75 P2RX7 (0.40)
SCHEMBL1479666 0.73
SCHEMBL8057994 0.71
SCHEMBL158178 0.71
SCHEMBL1179705 0.71
SCHEMBL3075701 0.69 BAZ2B (0.50)
SCHEMBL453733 0.69
SCHEMBL30438706 0.69
SCHEMBL5411092 0.69 CES2 (0.54)
Hydrochloric Acid SCHEMBL25337662 0.69 P2RX7 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836100-A Perovskite solar cell without hole transport layer based on copper halide chelate additive and preparation method 东方电气长三角(杭州)创新研究院有限公司 2025-04-15 CN claimed
EP-4423083-A2 SYNTHESIS OF PYRAZOLONE DERIVATIVE COMPOUNDS AND THEIR EFFECTS ON COX ENZYMES Istanbul Medipol Universitesi (TR) 2024-09-04 EP claimed
WO-2023096623-A2 SYNTHESIS OF PYRAZOLONE DERIVATIVE COMPOUNDS AND THEIR EFFECTS ON COX ENZYMES İSTANBUL MEDİPOL ÜNİVERSİTESİ (TR) 2023-06-01 WO claimed
CN-119836100-A Perovskite solar cell without hole transport layer based on copper halide chelate additive and preparation method 东方电气长三角(杭州)创新研究院有限公司 2025-04-15 CN disclosed
EP-4423083-A2 SYNTHESIS OF PYRAZOLONE DERIVATIVE COMPOUNDS AND THEIR EFFECTS ON COX ENZYMES Istanbul Medipol Universitesi (TR) 2024-09-04 EP disclosed
WO-2024034565-A1 IMIDAZOLYLAZOLE COMPOUND AND PEST CONTROL AGENT 日本曹達株式会社 2024-02-15 WO disclosed
WO-2023096623-A2 SYNTHESIS OF PYRAZOLONE DERIVATIVE COMPOUNDS AND THEIR EFFECTS ON COX ENZYMES İSTANBUL MEDİPOL ÜNİVERSİTESİ (TR) 2023-06-01 WO disclosed
US-10561676-B2 Method for treating cancer using dual antagonists of CXCR1 and CXCR2 SYNTRIX BIOSYSTEMS INC. (US) 2020-02-18 US disclosed
US-10130645-B2 Use of thiopyrimidinecarboxamide for treating cancer SYNTRIX BIOSYSTEMS, INC. (US) 2018-11-20 US disclosed
US-10130645-B2 Use of thiopyrimidinecarboxamide for treating cancer SYNTRIX BIOSYSTEMS, INC. (US) 2018-11-20 US disclosed
US-20180319786-A1 INHIBITOR OF THE P2X7 RECEPTOR MINDIMMUNE THERAPEUTICS, INC. 2018-11-08 US disclosed
EP-0630244-B1 MUSCARINIC AGONISTS UNIV TOLEDO (US) 1999-12-01 EP disclosed
EP-0652874-A1 2-HETEROCYCLIC-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS WARNER-LAMBERT COMPANY (US) 1995-05-17 EP disclosed
US-5403845-A Cognition activators; Alzheimer*s disaease UNIVERSITY OF TOLEDO (US) 1995-04-04 US disclosed
EP-0630244-A1 MUSCARINIC AGONISTS THE UNIVERSITY OF TOLEDO (US) 1994-12-28 EP disclosed
EP-0630244-A4 MUSCARINIC AGONISTS. UNIV TOLEDO (US) 1994-04-07 EP disclosed
WO-1993003726-A1 MUSCARINIC AGONISTS THE UNIVERSITY OF TOLEDO (US) 1993-03-04 WO disclosed
US-5175166-A Cognition activators THE UNIVERSITY OF TOLEDO (US) 1992-12-29 US disclosed
EP-0248735-B1 2-Thiazolyl imidazo [1,2-a] pyrimidines and their salts, process for their preparation, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed
EP-0248735-A1 2-Thiazolyl imidazo [1,2-a] pyrimidines and their salts, process for their preparation, their use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1987-12-09 EP disclosed