Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22491762 | 0.94 | FFAR1 (0.55) | FFAR1SLC6A3SLC6A2SLC6A4FFAR2 | |
| SCHEMBL14797824 | 0.94 | FFAR1 (0.55) | FFAR1SLC6A3SLC6A2SLC6A4FFAR2 | |
| Hydrochloric Acid SCHEMBL22491792 | 0.93 | FFAR1 (0.54) | FFAR1SLC6A3SLC6A2SLC6A4FFAR2 | |
| Hydrochloric Acid SCHEMBL22491794 | 0.93 | FFAR1 (0.54) | FFAR1SLC6A3SLC6A2SLC6A4FFAR2 | |
| SCHEMBL29743257 | 0.82 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL13471811 | 0.82 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL23493508 | 0.81 | FFAR1 (0.42) | FFAR1SLC6A3SLC6A2SLC6A4FFAR2 | |
| SCHEMBL29573070 | 0.80 | FFAR1 (0.46) | FFAR1FFAR2 | |
| SCHEMBL23509596 | 0.79 | FFAR1 (0.38) | FFAR1SLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4249915 | 0.77 | FFAR1 (0.60) | FFAR1SLC6A3SLC6A2SLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377417-B2 | Branched 3-phenylpropionic acid derivatives and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2022-07-05 | — | — | US | disclosed |
| US-20200385335-A1 | BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2020-12-10 | — | — | US | disclosed |
| US-20190185415-A1 | BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-06-20 | — | — | US | disclosed |
| US-10259776-B2 | Branched 3-phenylpropionic acid derivatives and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-04-16 | — | — | US | disclosed |
| US-20180282262-A1 | BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-10-04 | — | — | US | disclosed |
| US-10023528-B2 | Branched 3-phenylpropionic acid derivatives and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-07-17 | — | — | US | disclosed |
| US-20160264515-A1 | Branched 3-phenylpropionic acid derivatives and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| US-20140309307-A1 | Branched 3-phenylpropionic acid derivatives and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-16 | — | — | US | disclosed |
| US-8796335-B2 | Branched 3-phenylpropionic acid derivatives and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20130079412-A1 | Branched 3-phenylpropionic acid derivatives and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264515-A1 | Branched 3-phenylpropionic acid derivatives and their use | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
| US-20130079412-A1 | Branched 3-phenylpropionic acid derivatives and their use | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
| US-11377417-B2 | Branched 3-phenylpropionic acid derivatives and their use | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
| US-20190185415-A1 | BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
| US-20140309307-A1 | Branched 3-phenylpropionic acid derivatives and their use | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
| US-20200385335-A1 | BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
| US-10259776-B2 | Branched 3-phenylpropionic acid derivatives and their use | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
| US-10023528-B2 | Branched 3-phenylpropionic acid derivatives and their use | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
| US-20180282262-A1 | BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE | PC, FABP3, PCCA | FFAR1 210/4885SLC6A3 987/4885SLC6A2 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.