SCHEMBL1479837

SCHEMBL1479837

Cc1cc(Cl)ccc1-c1cccc2c1-c1ccccc1C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.43
DRD2 P14416 4/20 0.40
DRD4 P21917 4/20 0.40
CNR1 P21554 1/20 0.40
ITGA1 P56199 1/20 0.39
CASP6 P55212 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAOA P21397 2/20 0.37
ADRA2A P08913 1/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2C P28335 1/20 0.37
SLC6A4 P31645 1/20 0.37
HTR2B P41595 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23340052 0.78 MAOA (0.41) CYP1A2DRD2DRD4CNR1CASP6
SCHEMBL1481107 0.78 CNR1 (0.51) CYP1A2DRD2DRD4CNR1ITGA1
SCHEMBL28004757 0.77 MAOA (0.54) DRD2DRD4CASP6KDM4ENPC1
SCHEMBL31497079 0.76 HSP90AA1 (0.46) CYP1A2DRD2DRD4CNR1ITGA1
SCHEMBL25593987 0.76 CASP6 (0.44) CNR1CASP6NPC1RAB9ASMN1; SMN2
SCHEMBL13176936 0.75 NPC1 (0.49) CYP1A2CNR1KDM4ENPC1ALDH1A1
SCHEMBL30984364 0.75 NPC1 (0.49) CYP1A2CNR1KDM4ENPC1ALDH1A1
SCHEMBL28004759 0.75 MAOA (0.52) DRD2DRD4CASP6KDM4ENPC1
SCHEMBL22150253 0.75 CNR1 (0.44) CYP1A2CNR1CASP6NPC1RAB9A
SCHEMBL19299612 0.74 S100A4 (0.58) CYP1A2ITGA1KDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed