SCHEMBL1479862

SCHEMBL1479862

O=C1c2cc(-c3ccc(F)cc3)ccc2-c2ccc(-c3ccc(F)cc3)cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 5/20 0.50
MAPT P10636 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PTPN1 P18031 2/20 0.50
MEN1 O00255 1/20 0.50
APAF1 O14727 1/20 0.50
LMNA P02545 1/20 0.50
THRB P10828 1/20 0.50
XBP1 P17861 1/20 0.50
PTBP1 P26599 1/20 0.50
HTT P42858 1/20 0.50
GALK1 P51570 1/20 0.50
BLM P54132 1/20 0.50
SMAD3 P84022 1/20 0.50
KMT2A Q03164 1/20 0.50
ATM Q13315 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480728 0.92 NPC1 (0.63) PTPRCMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL30479662 0.80 CA1 (0.52) PTPRCPTPN1ALDH1A1MAOBPGR
SCHEMBL7432075 0.80 CA1 (0.52) PTPRCPTPN1ALDH1A1MAOBPGR
SCHEMBL30481072 0.79 NPC1 (0.76) PTPRCMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1480040 0.79 NPC1 (0.76) PTPRCMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL2350060 0.79 NPC1 (0.76) PTPRCMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL31255810 0.77 NPC1 (0.54) PTPRCMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL31255811 0.77 NPC1 (0.54) PTPRCMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1481010 0.77 TDP2 (0.53) MAPTNPC1RAB9ASMN1; SMN2MEN1
SCHEMBL14252245 0.77 PGR (0.47) PTPRCMAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed