Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799432 | 1.00 | G6PC1 (0.39) | G6PC1ALDH1A1TSHRAOC3NPC1 | |
| SCHEMBL15439105 | 0.90 | MEN1 (0.40) | G6PC1ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL15439103 | 0.90 | MEN1 (0.40) | G6PC1ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL14799568 | 0.87 | TSHR (0.41) | G6PC1ALDH1A1TSHRAOC3NPC1 | |
| SCHEMBL16492402 | 0.84 | G6PC1 (0.34) | G6PC1ALDH1A1TSHRAOC3NPC1 | |
| SCHEMBL14799194 | 0.84 | G6PC1 (0.34) | G6PC1ALDH1A1TSHRAOC3NPC1 | |
| SCHEMBL15440514 | 0.83 | NPC1 (0.36) | G6PC1ALDH1A1TSHRAOC3NPC1 | |
| SCHEMBL15440516 | 0.83 | NPC1 (0.36) | G6PC1ALDH1A1TSHRAOC3NPC1 | |
| SCHEMBL14799342 | 0.81 | G6PC1 (0.44) | G6PC1ALDH1A1TSHRAOC3HRH3 | |
| SCHEMBL14799345 | 0.81 | G6PC1 (0.44) | G6PC1ALDH1A1TSHRAOC3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |