Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439871 | 0.92 | ALDH1A1 (0.35) | TSHRALDH1A1AOC3G6PC1CA2 | |
| SCHEMBL14799430 | 0.87 | G6PC1 (0.39) | TSHRALDH1A1AOC3G6PC1CA2 | |
| SCHEMBL14799432 | 0.87 | G6PC1 (0.39) | TSHRALDH1A1AOC3G6PC1CA2 | |
| SCHEMBL14799194 | 0.86 | G6PC1 (0.34) | TSHRALDH1A1AOC3G6PC1CARM1 | |
| SCHEMBL16492402 | 0.86 | G6PC1 (0.34) | TSHRALDH1A1AOC3G6PC1CARM1 | |
| SCHEMBL14799345 | 0.83 | G6PC1 (0.44) | TSHRALDH1A1AOC3G6PC1CA2 | |
| SCHEMBL14799342 | 0.83 | G6PC1 (0.44) | TSHRALDH1A1AOC3G6PC1CA2 | |
| SCHEMBL15440157 | 0.82 | SORT1 (0.36) | TSHRALDH1A1AOC3G6PC1CA2 | |
| SCHEMBL15440516 | 0.82 | NPC1 (0.36) | TSHRALDH1A1AOC3G6PC1CA2 | |
| SCHEMBL15440514 | 0.82 | NPC1 (0.36) | TSHRALDH1A1AOC3G6PC1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |