Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440514 | 1.00 | NPC1 (0.36) | NPC1RAB9AALDH1A1TSHRCA2 | |
| SCHEMBL15440157 | 0.97 | SORT1 (0.36) | NPC1RAB9AALDH1A1TSHRCA2 | |
| SCHEMBL15439105 | 0.86 | MEN1 (0.40) | NPC1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL15439103 | 0.86 | MEN1 (0.40) | NPC1RAB9AALDH1A1TSHRKMT2A | |
| SCHEMBL15439871 | 0.85 | ALDH1A1 (0.35) | NPC1RAB9AALDH1A1TSHRCA2 | |
| SCHEMBL15439911 | 0.84 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1KMT2AGAA | |
| SCHEMBL15439912 | 0.84 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1KMT2AGAA | |
| SCHEMBL14799430 | 0.83 | G6PC1 (0.39) | NPC1RAB9AALDH1A1TSHRCA2 | |
| SCHEMBL14799432 | 0.83 | G6PC1 (0.39) | NPC1RAB9AALDH1A1TSHRCA2 | |
| SCHEMBL14799568 | 0.82 | TSHR (0.41) | NPC1RAB9AALDH1A1TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |