SCHEMBL14799647

SCHEMBL14799647

CCC(=O)c1ccc(Br)cc1CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.47
GAA P10253 3/20 0.42
MAPK1 P28482 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
DGAT1 O75907 1/20 0.39
HSD17B1 P14061 1/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
HPGD P15428 2/20 0.38
CES2 O00748 1/20 0.38
GALR3 O60755 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
ALDH1A1 P00352 1/20 0.37
PRNP P04156 1/20 0.37
PPARG P37231 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27691400 0.87 HSP90AB1 (0.43) HSP90AB1GAAMAPK1POLBMAPT
SCHEMBL6511330 0.87 GSK3B (0.47) GAAMAPK1MAPTRAB9ADGAT1
SCHEMBL22305152 0.85 MAPT (0.43) HSP90AB1GAAMAPK1POLBMAPT
SCHEMBL10689717 0.84 HSP90AB1 (0.45) HSP90AB1GAAMAPK1POLBMAPT
SCHEMBL24556551 0.83 HSP90AB1 (0.40) HSP90AB1GAAMAPK1POLBMAPT
SCHEMBL257249 0.82 KDM4E (0.50) POLBMAPTRAB9ACYP1A2CYP2C9
SCHEMBL6513432 0.82 HSD17B1 (0.56) MAPK1MAPTRAB9ADGAT1HSD17B1
SCHEMBL6174178 0.82 HSP90AB1 (0.48) HSP90AB1GAAPOLBMAPTRAB9A
SCHEMBL7534898 0.81 HSP90AB1 (0.67) HSP90AB1GAAPOLBMAPTRAB9A
SCHEMBL30863507 0.81 HSP90AB1 (0.67) HSP90AB1GAAPOLBMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 US disclosed
EP-2760941-A2 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY Nitto Denko Corporation (JP) 2014-08-06 EP disclosed
WO-2013049062-A2 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-04-04 WO disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 HSP90AB1 3163/4885GAA 2084/4885MAPK1 4693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.