Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206015 | 0.87 | POLB (0.47) | KDM4EGLAPOLBMYCNR4A1 | |
| SCHEMBL696316 | 0.85 | ALDH1A1 (0.50) | KDM4EGLAPOLBMYCNR4A1 | |
| SCHEMBL3746157 | 0.84 | PTGDR2 (0.53) | KDM4EGLAPOLBMYCNR4A1 | |
| SCHEMBL31125276 | 0.84 | KDM4E (0.55) | KDM4EGLAPOLBMYCNR4A1 | |
| SCHEMBL1500169 | 0.84 | KDM4E (0.50) | KDM4EGLAPOLBMYCNR4A1 | |
| SCHEMBL23243427 | 0.84 | KDM4E (0.55) | KDM4EGLAPOLBMYCNR4A1 | |
| SCHEMBL6513432 | 0.84 | HSD17B1 (0.56) | RXFP1PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11151739 | 0.84 | GABRP (0.51) | KDM4EGLAPOLBMYCNR4A1 | |
| SCHEMBL29907952 | 0.83 | NHERF1 (0.49) | KDM4EPOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1674351 | 0.83 | KDM4E (0.46) | KDM4EGLAPOLBMYCNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891448-A | Preparation method of roflumilast intermediate III | 上海医药集团青岛国风药业股份有限公司 | 2023-10-17 | — | — | CN | claimed |
| EP-2516479-B1 | NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS | BASF CORP (US) | 2016-04-20 | — | — | EP | claimed |
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| EP-2516479-A2 | NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS | BASF Corporation (US) | 2012-10-31 | — | — | EP | claimed |
| US-8211819-B2 | Internal and external donor compounds for olefin polymerization catalysts | BASF CORPORATION (US) | 2012-07-03 | — | — | US | claimed |
| WO-2011084691-A2 | NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS | BASF CORPORATION (US) | 2011-07-14 | — | — | WO | claimed |
| US-20110152481-A1 | Internal and external donor compounds for olefin polymerization catalysts | BASF CATALYSTS LLC (US) | 2011-06-23 | — | — | US | claimed |
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | SIRONAX LTD (KY) | 2026-03-19 | — | — | US | disclosed |
| US-12551490-B2 | Heterocyclic modulators of lipid synthesis | SAGIMET BIOSCIENCES INC. (US) | 2026-02-17 | — | — | US | disclosed |
| CN-116891448-B | Preparation method of roflumilast intermediate III | 上海医药集团青岛国风药业股份有限公司 | 2026-02-03 | — | — | CN | disclosed |
| US-20260015743-A1 | MEDIATED HYDROGEN ANODE FOR USE IN REDUCTIVE ELECTROSYNTHESIS | WISCONSIN ALUMNI RES FOUND (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250368620-A1 | ARNT Degrading Compounds and Uses Thereof | CELGENE CORPORATION (US) | 2025-12-04 | — | — | US | disclosed |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| EP-0206635-A1 | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4526882-A | Contacting magnesium alcoholate and group II or group IIIA metal alkyl, treating with titanium halide and electron donor, comminuting, treating product with titanium halide, ethyl benzoate, aromatic acid ester | STANDARD OIL COMPANY (INDIANA) (US) | 1985-07-02 | — | — | US | disclosed |
| US-4316853-A | Insecticidal tetraorganotin compounds | M&T CHEMICALS INC. (US) | 1982-02-23 | — | — | US | disclosed |
| EP-0001717-B1 | INSECTICIDAL COMPOSITIONS CONTAINING TETRAORGANOTIN COMPOUNDS AND METHOD FOR USING SAME | M & T CHEMICALS, INC. (US) | 1981-11-04 | — | — | EP | disclosed |
| US-4212810-A | INSECTICIDES | M&T CHEMICALS INC. (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0001717-A2 | Insecticidal compositions containing tetraorganotin compounds and method for using same | M & T CHEMICALS, INC. (US) | 1979-05-02 | — | — | EP | disclosed |
| US-4138483-A | Insecticidal compositions containing certain tetraorganotin compounds and method for using same | M&T CHEMICALS INC. (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015743-A1 | MEDIATED HYDROGEN ANODE FOR USE IN REDUCTIVE ELECTROSYNTHESIS | HAO2, HACL2, HVCN1 | KDM4E 3823/4885GLA 3260/4885POLB 1207/4885 |
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | NAMPT, NNMT, SARM1 | KDM4E 3382/4885GLA 2057/4885POLB 1690/4885 |
| US-12551490-B2 | Heterocyclic modulators of lipid synthesis | FASN, FADS1, FADS2 | KDM4E 1054/4885GLA 4205/4885POLB 3427/4885 |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | KDM4E 1533/4885GLA 2251/4885POLB 2183/4885 |
| US-20250368620-A1 | ARNT Degrading Compounds and Uses Thereof | ARNT, AHR, NR1H2 | KDM4E 2453/4885GLA 2084/4885POLB 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.